Package: Mediana 1.0.9

Mediana: Clinical Trial Simulations

Provides a general framework for clinical trial simulations based on the Clinical Scenario Evaluation (CSE) approach. The package supports a broad class of data models (including clinical trials with continuous, binary, survival-type and count-type endpoints as well as multivariate outcomes that are based on combinations of different endpoints), analysis strategies and commonly used evaluation criteria.

Authors:Gautier Paux, Alex Dmitrienko.

Mediana_1.0.9.tar.gz
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Mediana.pdf |Mediana.html✨
Mediana/json (API)
NEWS

# Install 'Mediana' in R:
install.packages('Mediana', repos = c('https://gpaux.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/gpaux/mediana/issues

On CRAN:

Conda:

biostatisticsclinical-trial-simulationsclinical-trialssimulations

6.53 score 29 stars 39 scripts 249 downloads 2 mentions 35 exports 12 dependencies

Last updated 4 years agofrom:e3a7d7f492. Checks:9 OK. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKMar 28 2025
R-4.5-winOKMar 28 2025
R-4.5-macOKMar 28 2025
R-4.5-linuxOKMar 28 2025
R-4.4-winOKMar 28 2025
R-4.4-macOKMar 28 2025
R-4.4-linuxOKMar 28 2025
R-4.3-winOKMar 28 2025
R-4.3-macOKMar 28 2025

Exports:AdjustCIsAdjustPvaluesAnalysisModelAnalysisStackCriterionCSECustomLabelDataModelDataStackDesignEvaluationModelEventExtractAnalysisStackExtractDataStackfamiliesGenerateDataGenerateReportMultAdjMultAdjProcMultAdjStrategyOutcomeDistparametersPresentationModelProjectSamplesamplesSampleSizeSectionSimParametersStatisticstatisticsSubsectionTableTesttests

Dependencies:codetoolsdigestdoParalleldoRNGforeachiteratorslatticeMASSMatrixmvtnormrngtoolssurvival

Adjusted p-values and one-sided simultaneous confidence limits

Gautier Paux and Alex Dmitrienko

Rendered fromadjusted-pvalues.Rmdusingknitr::rmarkdownon Mar 28 2025.

Last update: 2019-01-14
Started: 2017-08-09

Case studies

Gautier Paux and Alex Dmitrienko

Rendered fromcase-studies.Rmdusingknitr::rmarkdownon Mar 28 2025.

Last update: 2019-03-06
Started: 2017-04-25

Mediana: an R package for clinical trial simulations

Gautier Paux and Alex Dmitrieniko

Rendered frommediana.Rmdusingknitr::rmarkdownon Mar 28 2025.

Last update: 2019-01-14
Started: 2017-04-25